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Tipepidine hydrochloride
CAS No. 1449686-84-3
Tipepidine hydrochloride( —— )
Catalog No. M23615 CAS No. 1449686-84-3
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
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| 5MG | 58 | In Stock |
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| 10MG | 87 | In Stock |
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| 25MG | 156 | In Stock |
|
| 50MG | 260 | In Stock |
|
| 100MG | 410 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTipepidine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionTipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
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DescriptionTipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
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In Vitro——
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In VivoAnimal Model:Male Wistar rats weighting 150-240 g (5-7 weeks old) Dosage:10, 20 and 40 mg/kg Administration:I.p.; 0.5, 5, 23 hours Result:Decreased the immobility time in the forced swimming test in ACTH-treated rats.
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Synonyms——
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorD2
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Research Area——
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Indication——
Chemical Information
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CAS Number1449686-84-3
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Formula Weight311.89
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Molecular FormulaC15H18ClNS2
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Purity>98% (HPLC)
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SolubilityDMSO:41.67 mg/mL (133.60 mM; Need ultrasonic)
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SMILESCN1C/C(CCC1)=C(C2=CC=CS2)\C3=CC=CS3.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hamasaki R, et al. Tipepidine activates VTA dopamine neuron via inhibiting dopamine D? receptor-mediated inward rectifying K? current. Neuroscience. 2013 Nov 12;252:24-34.
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